I didn't see any NPCs getting stuck or other navmesh related jankiness with them both enabled, but I would advise use one or the other. Riverwood is one of the first villages that the player can encounter as it is very close to the exit point of the introductory quest line.
He left a note, and his nice home to live in! By accessing I mean if I move the mouse over any of these 2 menus (their content to be more precise) when they are active. When logged in, you can choose up to 12 games that will be displayed as favourites in this menu.